Here is our 2nd Published Clinical Research Report in another Prestigious, Professional, Peer-Reviewed Medical Journal which Proves that the Ingredients in the New & Improved Hair Genesis Generation 4 Proprietary Formulations Work Better for Male & Female Hairloss
University Based Research Study Published in 2009
Recent University-Based Science Research Study ( First Dual Mechanism of Action Hairloss Product )
Inhibition of Inflammatory Gene Expression in Keratinocytes Using a Composition Containing Carnitine, Thioctic Acid and Saw Palmetto Extract
Researchers: Sridar Chittur1, Brian Parr1 and Geno Marcovici2
1 State University of New York (SUNY), Albany, NY
2 Advanced Restoration Technologies (Hair Genesis), Inc., Phoenix, AZ
Download Research Report
2nd Published Research Study using Hair Genesis Formulations
Chronic inflammation of the hair follicle is considered a contributing factor in the patho-genesis of AndroGenetic Alopecia (AGA).
Previously, we clinically tested LipoSterolic Extract of Serenoa repens (LSESr – Saw Palmetto) and its glycoside, Beta-Sitosterol, in subjects with AGA and showed a highly positive response to treatment. In the most recent University-based science study, we sought to determine whether blocking of inflammation using a composition containing LSESr as well as two Anti-Inflammatory agents (carnitine and thioctic acid) could alter the expression of molecular markers of inflammation in a well-established in vitro system.
Using a well-validated assay representative of hair follicle keratinocytes, specifically, stimulation of cultured human keratinocyte cells in vitro, we measured changes in gene expression of a spectrum of well-known inflammatory markers. Lipopolysaccharide (LPS) provided an inflammatory stimulus. In particular, we found that the composition effectively suppressed LPS-activated gene expression of chemokines, including CCL17, CXCL6 and LTB(4) associated with pathways involved in inflammation and apoptosis.
Our data supports the hypothesis that the test compound exhibits Anti-Inflammatory characteristics in a well-established in vitro assay representing hair follicle keratinocyte gene expression. These findings suggest that 5-Alpha Reductase inhibitors (5AR Inhibitors), also known as DHT Blockers, combined with blocking of inflammatory processes could represent a unique two-pronged approach (Dual Mechanism of Action) in the treatment of pattern hair loss with improved effectiveness over all other current hair loss treatment products.
Evidence Based Complementary Alternative Medicine (eCAM)
No other non-Drug / botanical hairloss treatment remedy has even One (1) research study published in a Peer-Reviewed Medical Journal. But now, Hair Genesis, is Supported by TWO (2) published research studies, including our recent landmark University-based study which led to the development of our newest and most effective Generation 4 formulations ever. Just published in 2009, in the prestigious Peer-Reviewed Medical Journal:
Read the Study: Evidence Based Complementary Alternative Medicine
National Institutes of Health & the US National Library of Medicine
Like our original landmark Published Study back in Year 2002, the results of this second break-through University based Research Study were then also professionally acknowledged and published by PubMed.gov (a service of the National Institutes of Health and the National Library of Medicine), one of the most respected and authoritative sources of published medical information online. (click a graphic below) Absolutely no other non-Drug / botanical hair loss treatment product can make this claim.